They will handle it fine. I used to run an M22 and M20 in my 3700 lb Chevelle when it had a 427 in it. Car ran in the mid to low 11s back then. There was breakage about once a year but this was with slicks. On the street they will be fine. When you run big tires that don't spin with about 400-500 horsepower, then it's Jerico time.
Jerry